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IMSI (intracytoplasmic morphologically-selected sperm injection) is a assisted reproductive technology (ART) used in IVF (in vitro fertilization) to select and inject sperm that have normal morphology. This technique utilizes a light microscope with magnification up to 6000 times, which allows embryologists to see the details of sperm morphology and evaluate the shape, size, and structure of the sperm head, neck, and tail.
In IMSI, embryologists can see the sperm morphology more accurately before the sperm is injected into the egg. This can increase the chances of successful fertilization and reduce the risk of miscarriage or genetic abnormalities in the embryo. IMSI can also help couples who have experienced failed fertilization with conventional ICSI techniques, as this technique allows for more specific and accurate sperm selection. Although IMSI is more expensive than conventional ICSI techniques, this technique can provide better results, especially for couples who have high DNA fragmentation sperm.